FitnessProsBooks.com - Mechanisms of Protein Folding

	List Price: $104.50 Our Price: Your Save: $ 104.50 ( 100% ) Availability: Manufacturer: Oxford University Press, USA
Average Customer Rating: [ not yet rated ]
Binding: Paperback Dewey Decimal Number: 572.6 EAN: 9780199637881 ISBN: 0199637881 Label: Oxford University Press, USA Manufacturer: Oxford University Press, USA Number Of Items: 1 Number Of Pages: 433 Publication Date: 2000-12-15 Publisher: Oxford University Press, USA Studio: Oxford University Press, USA
Related Items Introduction to Protein Structure: Second Edition Protein NMR Spectroscopy: Principles and Practice Structure and Mechanism in Protein Science: A Guide to Enzyme Catalysis and Protein Folding
Editorial Reviews: The process by which newly synthesized polypeptide chains become their final 3-dimensional protein forms is clearly explained, providing students and researchers of various backgrounds with both a conceptual and technical understanding of the subject. The new Second Edition incorporates the significant improvements in the field such as advances in interpreting observed kinetic data, the development of technology to observe fast folding reactions, the molten globule state, and the vital role of chaperone proteins in protein folding. The emphasis on experimental approaches has been maintained but this edition does so within the explicit context of simulations and energy surfaces. New discoveries of the central importance of protein folding and unfolding reactions in biology and medicine (including mutation and 'misfolding') are carefully explored. Three case studies elucidate the difficulties of studying protein folding in vivo.